737824-88-3

Upstream product

• 737823-20-0 N-(4-{2-[4-(hydroxymethyl)phenyl]ethyl}-1,3-thiazol-2-yl)acetamide 

Downstream Products

• 737824-89-4 N-(4-{2-[4-(cyanomethyl)phenyl]ethyl}-1,3-thiazol-2-yl)acetamide 
• 1174633-60-3 N-(4-{2-[4-(sulfanylmethyl)phenyl]ethyl}-1,3-thiazol-2-yl)acetamide 

Relevant academic research and scientific papers

THIAZOLE DERIVATIVE AND USE THEREOF AS VAP-1 INHIBITOR

The present invention provides a novel thiazole derivative useful as a VAP-1 inhibitor, a pharmaceutical agent for the prophylaxis or treatment of VAP-1 associated diseases and the like. A compound represented by the formula (I): wherein each symbol is as defined in the specification, or a pharmaceutically acceptable salt thereof.

THIAZOLE DERIVATIVES AND THEIR USE AS VAP-1 INHIBITORS

A compound of the formula (I): R1-NH-X-Y-Z (I) wherein R1 is acyl; X is a bivalent residue derived from optionally substituted thiazole; Y is a bond, lower alkylene or -COHN-; and Z is a groupe of the formulae (II) or (III) wherein R