73791-96-5Relevant academic research and scientific papers
Hexafluoroisopropanol and Acetyl Chloride Promoted Catalytic Hydroarylation with Phenols
Roy, Sudeshna,Motiwala, Hashim F.,Koshlap, Karl M.,Aubé, Jeffrey
supporting information, p. 306 - 315 (2017/12/07)
We report a catalytic hydroarylation method to convert phenols to dihydrocoumarins in hexafluoroisopropanol (HFIP) using acid generated from sub-stoichiometric amounts of acetyl chloride as catalyst. Attractive elements include easy set-up and isolation, and applicability to a range of phenols including natural product substrates.
Hydroarylation of cinnamic acid with phenols catalyzed by acidic ionic liquid [H-NMP]HSO4: computational assessment on substituent effect
Zadsirjan, Vahideh,Heravi, Majid M.,Tajbakhsh, Mahmoud,Oskooie, Hossein A.,Shiri, Morteza,Hosseinnejad, Tayebeh
, p. 6407 - 6422 (2016/07/06)
Hydroarylation of cinnamic acid with different substituted phenols, in the presence of acidic ionic liquid, N-methyl-2-pyrrolidonum hydrosulfate ([H-NMP]HSO4) gave the corresponding dihydrocoumarins in high yields and excellent selectivity. Amo
p-Toluenesulfonic acid mediated hydroarylation of cinnamic acids with anisoles and phenols under metal and solvent-free conditions
Jagdale, Arun R.,Sudalai, Arumugam
, p. 4895 - 4898 (2008/02/08)
Hydroarylation of cinnamic acids with anisoles and phenols mediated by p-toluenesulfonic acid (p-TSA) under metal and solvent-free conditions gave 3-(4-methoxyphenyl)-3-phenylpropanoic acids and dihydrocoumarins, respectively, in high yields and excellent selectivity.
Smooth muscle spasmolytic agents
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, (2008/06/13)
The present invention relates to smooth muscle spasmolytic agents, pharmaceutical compositions containing them and method of using said compounds and compositions for the treatment of urinary incontinence, and other smooth muscle contractility conditions. More particularly, the present invention relates to certain metabolically stabilized secondary amines having smooth muscle relaxing properties while avoiding, on administration to a mammal, adverse side effects such as prominent antimuscarinic, arrhythmogenic and cardiodepressive effects.
