73794-65-7Relevant academic research and scientific papers
Reactions of Electron Deficient Dienes with (Acylmethylene)triphenylphosphoranes: One-Pot-Three-Step-Reactions
Flitsch, Wilhelm,Gesing, Ernst Rudolf F.
, p. 3146 - 3153 (2007/10/02)
3a-Azaazulenes (1, 7) react with (acylmethylene)triphenylphosphoranes (2) in a one-pot-three-step-synthesis (Michael addition, intramolecular addition, Wittig elimination) to form cyclohexadiene 1,4-derivatives (3, 8).The course of the reaction is determined by steric requirements which is shown by ethyl 3-isopropylbenzoate (11) formation from ethyl 1,3-cyclohexadiene-1-carboxylate (9) and phosphorane 2b.
