7380-85-0

Basic information

• Product Name: Sulfonium, dimethyl-, 2-(4-bromophenyl)-2-oxoethylide
• CAS NO: 7380-85-0
• Molecular Formula: C10H11BrOS
• Molecular Weight: 259.167
• Mol File: 7380-85-0.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: Sulfonium, dimethyl-, 2-(4-bromophenyl)-2-oxoethylide(CAS DataBase Reference)
• NIST Chemistry Reference: Sulfonium, dimethyl-, 2-(4-bromophenyl)-2-oxoethylide(7380-85-0)
• EPA Substance Registry System: Sulfonium, dimethyl-, 2-(4-bromophenyl)-2-oxoethylide(7380-85-0)

Safety Data

• Hazardous Substances Data: 7380-85-0(Hazardous Substances Data)

Upstream product

• 75-18-3 dimethylsulfide 
• 99-73-0 para-bromophenacyl bromide 
• 6047-83-2 (4-bromophenacyl)dimethylsulfanium bromide 

Downstream Products

• 14966-77-9 6-(4-bromo-phenyl)-3,4-diphenyl-2H-pyran-2-one 
• 1173097-23-8 C₂F₃O₂^(1-)*C₁₀H₁₂BrOS⁽¹⁺⁾ 
• 132278-63-8 (5S)-5-benzyl-2,2,3-trimethylimidazolidin-4-one 
• 1173097-22-7 1-(4-bromophenyl)-3,3-bis(4-(dimethylamino)phenyl)-2-(dimethyl-λ⁴-sulfanylidene)propan-1-one 
• 1428732-90-4 [mercury(II)(chloride)2(CH(SMe₂)C(O)C₆H₄Br)]2 
• 1428732-91-5 [mercury(II)(bromide)2(CH(SMe₂)C(O)C₆H₄Br)]2 
• 1380095-28-2 (4R,5S)-5-(4-bromobenzoyl)-4-(2-methoxyphenyl)oxazolidin-2-one 
• 1332363-59-3 (3S,4S)-3-(3-(4-bromophenyl)-3-oxopropyl)-4,6-diphenyl-3,4-dihydro-2H-pyran-2-one 

Relevant articles and documents

Visible-Light-Promoted Polysubstituted Olefins Synthesis Involving Sulfur Ylides as Carbene Trapping Reagents

A blue-light-emitting diode (LED) promoted coupling of aryl diazoacetates with sulfur ylides is described. This protocol features mild conditions, good functional group tolerance, and broad substrate scope for both aryl diazoacetates with sulfur ylides. Under optimal reaction conditions, a wide range of trisubstituted olefins is obtained in moderate to good yield, which can be further transferred to other biologically important heterocycles after a two-step simple operation.

1,6-Conjugated Addition-Mediated [2+1] Annulation: Approach to Spiro[2.5]octa-4,7-dien-6-one

A formal 1,6-conjugated addition-mediated [2+1] annulation to synthesize spiro[2.5]octa-4,7-dien-6-one with p-quinone methides and sulfur ylides has been described. This domino-type process was highly diastereoselective and exhibited good functional group tolerance and scalability without the use of metals and bases.

Reactivity of mercury(II) halides with the α-keto stabilized sulfonium ylides: Crystal structures of two new polymer and binuclear complexes and in vitro antibacterial study

Reaction of α-keto stabilized sulfonium ylides (Me) 2SCHC(O)C6H4R (R = p-NO2 (Y) and p-Br(Y′)) with HgX2 (X = Cl, Br and I) in equimolar ratios using methanol as solvent leads to two types of products. Single crystal X-ray diffraction analysis reveals (i) binuclear complex of [HgI2(Y)] 2 (3) with an asymmetric halide-bridged structure and (ii) one-dimensional polymer of [HgI2(Y′)]n (6) that the monomeric -Hg-I-Hg- bridging leads to a zig-zag polymeric chain in which mercury assumes a distorted tetrahedral geometry. Characterization of the compounds by IR, 1H and 13C NMR spectroscopy confirmed coordination of the ylide to the metal through the carbon atom. Analytical data indicate a 1:1 stoichiometry between the ylide and Hg(II) halide in all of products. The Hg(II) complexes with different ligands evaluated for their antibacterial activity using disc diffusion method. The results show that all complexes represent antibacterial activity against bacteria tested especially on Gram positive ones.