73844-91-4

Upstream product

• 75159-10-3 N-(4-methylbenzylidene)-p-toluenesulfonamide 
• 104-87-0 4-methyl-benzaldehyde 
• 70-55-3 toluene-4-sulfonamide 

Downstream Products

• 923569-32-8 (R)-adamantan-1-yl 2-hydroxy-1-oxo-2,3-dihydro-1H-indene-2-carboxylate 
• 75159-10-3 N-(4-methylbenzylidene)-p-toluenesulfonamide 
• 791-28-6 Triphenylphosphine oxide 
• 1445979-91-8 N-((2S,5S)-5-benzyl-4-oxo-2-(p-tolyl)-3-tosyloxazolidin-5-yl)benzamide 

Relevant academic research and scientific papers

Lewis acids promoted 3 + 2 cycloaddition of oxaziridines and cyclic allylic alcohols through carbonyl imine intermediates

Syntheses of isoxazolidines through the carbonyl imine intermediates are currently limited to monosubstituted olefin substrates. Herein, we reported syntheses of novel bicyclic isoxazolidine-containing compounds through 1,3-dipolar cycloaddition reactions

Chemistry of Oxaziridines. 1. Synthesis and Structure of 2-Arenesulfonyl-3-aryloxaziridines. A New Class of Oxaziridines

A new class of oxaziridine derivatives, 2-arenesulfonyl-3-aryloxaziridines (2), is prepared by m-CPBA oxidation of sulfonimines (RSO2N=CHAr).These compounds are the first stable examples of this ring system to have a substituent other than carbon attached to nitrogen and are characterized by a highly electrophilic oxaziridine oxygen atom.These oxaziridines have the E configuration as determined by X-ray crystallography.The presence of the powerful electron-attracting sulfonyl group attached to nitrogen apparently has little effect on the structure of the oxaziridine three-membered ring.Of more significance are the observations that the nitrogen lone pair in 2 is opposite to one of the sulfonyl oxygens and that the long S-N bond length implies little if any conjugative interaction between sulfur and nitrogen.Attempts to prepare oxaziridines via oxidation of sulfonimines, 5, derived from acetophenone gave imidoyl ether 14, a novel Baeyer-Villiger oxidation product of a C-N double bond.