Uridine, 5-[2-(3-aminophenyl)ethenyl]-2'-deoxy-, (E)-, also known as 5-[2-(3-aminophenyl)vinyl]-2'-deoxyuridine or 5-Ethynyl-2'-deoxyuridine (EdU), is a nucleoside analog that is structurally similar to thymidine. It is a modified form of deoxyuridine, with an ethynyl group (-C≡CH) replacing the methyl group at the 5-position of the uracil base. EdU is commonly used in molecular biology and cell biology as a thymidine analog for DNA synthesis, allowing for the detection and quantification of DNA replication in living cells. It is particularly useful in applications such as cell proliferation assays, DNA repair studies, and the analysis of cell cycle dynamics. The (E)- configuration in the name refers to the geometric isomerism of the double bond in the ethynyl group, which is important for its chemical properties and reactivity.
The CAS Registry Mumber 73847-54-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,3,8,4 and 7 respectively; the second part has 2 digits, 5 and 4 respectively. Calculate Digit Verification of CAS Registry Number 73847-54: (7*7)+(6*3)+(5*8)+(4*4)+(3*7)+(2*5)+(1*4)=158 158 % 10 = 8 So 73847-54-8 is a valid CAS Registry Number.