73852-17-2

Basic information

• Product Name: 2,6-DICHLOROPHENYLBORONIC ACID
• Synonyms: RARECHEM AH PB 0089;2,6-DICHLOROPHENYLBORONIC ACID;2,6-DICHLOROBENZENEBORONIC ACID;AKOS BRN-0086;2,6-Dichlorophenylboronic;3,6-DICHLOROPHENYLBORONICACID;2,6-Dichlorophenylboronic Acid (contains varying amounts of Anhydride);2,6-Dichlorophenylboronic acid,98%
• CAS NO: 73852-17-2
• Molecular Formula: C₆H₅BCl₂O₂
• Molecular Weight: 190.82
• EINECS: -0
• Product Categories: blocks;BoronicAcids;Aryl;Boronic acid;Organoborons;B (Classes of Boron Compounds);Boronic Acids;Boronate Ester;Potassium Trifluoroborate
• Mol File: 73852-17-2.mol
• Article Data: 5

Chemical Properties

• Melting Point: 153 °C
• Boiling Point: 341.8 °C at 760 mmHg
• Flash Point: 160.5 °C
• Appearance: Off-white/Powder
• Density: 1.47 g/cm³
• Vapor Pressure: 3.03E-05mmHg at 25°C
• Refractive Index: 1.577
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• PKA: 7.94±0.58(Predicted)
• Water Solubility: Insoluble in water.
• BRN: 4802506
• CAS DataBase Reference: 2,6-DICHLOROPHENYLBORONIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-DICHLOROPHENYLBORONIC ACID(73852-17-2)
• EPA Substance Registry System: 2,6-DICHLOROPHENYLBORONIC ACID(73852-17-2)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 36/37/38-22-36
• Safety Statements: 26-36-37/39
• HazardClass: IRRITANT
• Hazardous Substances Data: 73852-17-2(Hazardous Substances Data)

Usage

Chemical Properties

Off-white Cryst

Uses

Different sources of media describe the Uses of 73852-17-2 differently. You can refer to the following data:
1. suzuki reaction
2. Reagent used for palladium-catalyzed stille and suzuki-miyaura cross-couplings, palladium (pd)-catalytized reactions. Reagent used in preparation of common building blocks for pharmaceuticals and agrochemicals.

InChI:InChI=1/C6H5BCl2O2/c8-4-2-1-3-5(9)6(4)7(10)11/h1-3,10-11H

Upstream product

• 19393-92-1 1-bromo-2,6-dichlorobenzene 
• 121-43-7 Trimethyl borate 
• 688-74-4 boric acid tributyl ester 
• 150-46-9 triethyl borate 
• 7732-18-5 water 
• 541-73-1 1,3-Dichlorobenzene 
• 108-86-1 bromobenzene 

Downstream Products

• 867333-31-1 7-(2,6-dichlorophenyl)-5-methyl-1,2,4-benzotriazine-3-ylamine 
• 623144-23-0 6-(benzyloxy)-2-(2,6-dichlorophenyl)quinoline 

Relevant articles and documents

Preparation method of 2, 6-dichlorophenylboronic acid

The invention discloses a preparation method of 2, 6dichlorophenylboronic acid, which belongs to the technical field of fine processing, and mainly comprises the following steps: adding magnesium chips into 2bromo 1, 3dichlorobenzene used as a raw material to prepare a Grignard reagent, reacting with trialkyl borate, and carrying out acidic hydrolysis to obtain a 2, 6dichlorophenylboronic acid crude product; and finally, recrystallizing and purifying to obtain pure 2, 6-dichlorophenylboronic acid. The preparation method is simple, raw materials are easy to obtain, and the method is suitable for large-scale industrial production.

Moisture-Tolerant Frustrated Lewis Pair Catalyst for Hydrogenation of Aldehydes and Ketones

In this paper, we report on the development of a bench-stable borane for frustrated Lewis pair catalyzed reduction of aldehydes, ketones, and enones. The deliberate fine-tuning of structural and electronic parameters of Lewis acid component and the choice of Lewis base provided for the first time, a moisture-tolerant FLP catalyst. Related NMR and DFT studies underpinned the unique behavior of this FLP catalyst and gave insight into the catalytic activity of the resulting FLP catalyst.