73855-60-4

Usage

InChI:InChI=1/C11H9NO2S2/c1-14-8-5-3-2-4-7(8)6-9-10(13)12-11(15)16-9/h2-6H,1H3,(H,12,13,15)/b9-6-

Upstream product

• 141-84-4 2-thioxo-4-thiazolidinone 
• 135-02-4 ortho-anisaldehyde 

Downstream Products

• 65562-25-6 5-(2-methoxy-benzylidene)-3-(tetra-O-acetyl-β-D-glucopyranosyl)-2-thioxo-thiazolidin-4-one 
• 76979-49-2 5-(2-methoxyphenylmethylene)-2-morpholino-4-oxo-2-thiazolidine 
• 36946-71-1 5-(2-Methoxyphenylmethylene)-2-imino-4-thiazolidinone 
• 36937-40-3 5-(2-methoxyphenylmethylene)-2-piperidino-4-oxo-2-thiazoline 
• 76979-33-4 5-[1-(2-Methoxy-phenyl)-meth-(E)-ylidene]-2-methylsulfanyl-thiazol-4-one 
• 76979-37-8 5-(2-methoxyphenylmethylene)-3-methyl-4-oxo-2-thioxothiazolidine 
• 81180-04-3 piperidine salt of (E,Z)-5-(2-methoxyphenylmethylene)-4-oxo-2-thioxothiazolidine 
• 50459-63-7 5-(2-methoxy-benzylidene)-thiazolidine-2,4-dione 2-hydrazone 
• 50459-64-8 benzaldehyde [5-(2-methoxy-benzylidene)-4-oxo-thiazolidin-2-ylidene]-hydrazone 
• 42056-18-8 3-(2-methoxyphenyl)-2-sulfanylpropenoic acid 

Relevant academic research and scientific papers

Introducing broadened antibacterial activity to rhodanine derivatives targeting enoyl-acyl carrier protein reductase

Broadened antibacterial activity was introduced to rhodanine derivatives targeting Mycobacterial tuberculosis enoyl-acyl carrier protein reductase (Mtb InhA) by recruiting feature of xacins to bring DNA Gyrase B inhibitory capability. This is significant for preventing further bacterial injections in the tuberculosis treatment. The most potent compound Cy14 suggested comparable bioactivity (IC50=3.18μM for Mtb InhA; IC50=10nM for DNA Gyrase B) with positive controls. Structure–activity relationship discussion and molecular docking model revealed the significance of rhodanine moiety and derived methoxyl on meta-position, pointing out orientations for future modification.

Combination of 4-anilinoquinazoline and rhodanine as novel epidermal growth factor receptor tyrosine kinase inhibitors

Abstract A type of novel rhodanine-based 4-anilinoquinazoline, which designed the combination between quinazoline as the backbone and various substituted biological rhodanine groups as the side chain, have been synthesized, and their antiproliferative act

Facile and convenient synthesis of 5-arylalkylidenerhodanines by electrocatalytic crossed aldol condensation

An electrochemically induced catalytic crossed Aldol condensation of one equivalent of rhodanine with various aromatic aldehydes and ketones in ethanol in an undivided cell in the presence of sodium bromide as an electrolyte results in the formation of th

New structural features in triphenylphosphinesilver(I) sulfanylcarboxylates

We investigated the reactions of 1.5 : 1 : 1 mole ratio mixtures of triphenylphosphine, silver nitrate and 3-(aryl)-2-sulfanylpropenoic acids H 2xspa in chloroform/water, where in the acid nomenclature, spa = 2-sulfanylpropenoato and x = p, Clp