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6-Hydroxy-2-azabicyclo[2.2.2]octane hydrochloride, commonly known as lobeline, is a hydrochloride salt of a natural alkaloid derived from plants of the Lobelia genus. This chemical compound possesses potential pharmacological effects and has been the subject of research for its possible applications in smoking cessation and Parkinson's disease treatment.

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  • 738551-49-0 Structure
  • Basic information

    1. Product Name: 6-Hydroxy-2-azabicyclo[2.2.2]octane hydrochloride
    2. Synonyms: 6-Hydroxy-2-azabicyclo[2.2.2]octane hydrochloride
    3. CAS NO:738551-49-0
    4. Molecular Formula: C7H14ClNO
    5. Molecular Weight: 163.64516
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 738551-49-0.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 6-Hydroxy-2-azabicyclo[2.2.2]octane hydrochloride(CAS DataBase Reference)
    10. NIST Chemistry Reference: 6-Hydroxy-2-azabicyclo[2.2.2]octane hydrochloride(738551-49-0)
    11. EPA Substance Registry System: 6-Hydroxy-2-azabicyclo[2.2.2]octane hydrochloride(738551-49-0)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 738551-49-0(Hazardous Substances Data)

738551-49-0 Usage

Uses

Used in Smoking Cessation Applications:
6-Hydroxy-2-azabicyclo[2.2.2]octane hydrochloride is used as a smoking cessation aid for its ability to interact with the same receptors in the brain as nicotine. This interaction may help reduce cravings and withdrawal symptoms associated with nicotine dependence, thereby assisting individuals in quitting smoking.
Used in Parkinson's Disease Treatment:
In the field of neurology, 6-Hydroxy-2-azabicyclo[2.2.2]octane hydrochloride is used as a potential treatment for Parkinson's disease due to its demonstrated capacity to increase dopamine levels in the brain. This increase in dopamine may help alleviate some of the motor symptoms associated with the disease, although further research is necessary to fully understand its potential benefits and risks.

Check Digit Verification of cas no

The CAS Registry Mumber 738551-49-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,3,8,5,5 and 1 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 738551-49:
(8*7)+(7*3)+(6*8)+(5*5)+(4*5)+(3*1)+(2*4)+(1*9)=190
190 % 10 = 0
So 738551-49-0 is a valid CAS Registry Number.

738551-49-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-aza-bicyclo[2.2.2]octan-6-ol

1.2 Other means of identification

Product number -
Other names endo-2-azabicyclo[2.2.2]-octan-6-ol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:738551-49-0 SDS

738551-49-0Upstream product

738551-49-0Downstream Products

738551-49-0Relevant articles and documents

5-(1,1-Diphenyl-3-(5- or 6-hydroxy-2-azabicyclo(2.2.2)oct-2-yl)propyl)-2-alkyl-1,3,4-oxadiazoles and related compounds

-

, (2008/06/13)

This invention encompasses novel 5-[1,1-diphenyl-3-(5-or 6-hydroxy-2-azabicyclo[2.2.2]oct-2-yl)propyl]-2-alkyl-1,3,4-oxadiazoles and their lower O-alkanoyl derivatives. These compounds are useful anti-diarrheal agents and also possess little or no analges

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