73867-36-4

Upstream product

• 104-01-8 4-Methoxyphenylacetic acid 
• 613-45-6 2,4-Dimethoxybenzaldehyde 

Downstream Products

• 531-95-3 equol 
• 1383121-29-6 (S)-3-(2,4-dimethoxyphenyl)-2-(4-methoxyphenyl)propionic acid 
• 1383121-33-2 (S)-4-(3-bromo-2-(4-hydroxyphenyl)propyl)benzene-1,3-diol 
• 1057663-20-3 (S)-1-(3-bromo-2-(4-methoxyphenyl)propyl)-2,4-dimethoxy-benzene 
• 1057663-19-0 (S)-3-(2,4-dimethoxyphenyl)-2-(4-methoxyphenyl)propan-1-ol 
• 1838-44-4 2-(4-'methoxyphenyl)-6-methoxybenzo[b]furan 
• 73867-55-7 (Z)-α-acetoxy-2',4,4'-trimethoxystilbene 
• 73867-56-8 2-acetoxy-1-(4-methoxyphenyl)-2-(2,4-dimethoxyphenyl)ethanone 

Relevant academic research and scientific papers

Enantioselective iridium-catalyzed hydrogenation of α-arylcinnamic acids and synthesis of (S)-equol

By using iridium catalyst based on chiral spiro phosphine-oxazoline ligands, the hydrogenation of α-arylcinnamic acids was accomplished under ambient pressure and low catalyst loading (as low as 0.01 mol %), providing useful 2,3-diarylpropionic acids in high yields with excellent enantioselectivities (up to 99% ee). A catalytic enantioselective synthesis of (S)-equol with the present hydrogenation reaction as a key step was accomplished starting from commercially available starting materials in six steps with 48.4% overall yield.

The Oxidation of (E)-α-Phenylcinnamic Acids with Manganese(III) Acetate

The oxidation of eight (E)-α-phenylcinnamic acids with manganese(III) acetate in boiling acetic acid containing acetic anhydride gave 3-phenylcoumarins, 3-phenyl-1-oxaspirodeca-3,7,9-triene-2,6-diones, 2-phenylbenzofurans, 3-(acetoxymethyl)-2-phenylbenzofurans, 3-formyl-2-phenylbenzofuran, 2-acetoxy-2-phenyl-3(2H)-benzofuranones, (Z)-Α-acetoxystilbenes, 2-acetoxy-1,2-diphenylethanones, 5-acetoxy-4,5-diphenyl-2(5H)-furanones, and diphenylacetylene.Tha reaction pathways are discussed.