7390-86-5Relevant academic research and scientific papers
Homo-condensation of acetophenones toward imidazothiones
Bui, Thuy Thu,Nguyen, Tung Thanh,Pham, Phuc Hoang,Son Phan, Nam Thanh,Thien Nguyen, Phuc Thai,Tra, Hien Nhat
, p. 40225 - 40228 (2020)
Direct synthesis of imidazothiones from simple, commercial substrates is not known. We report a method for the condensation of acetophenones, elemental sulfur, and ammonium acetate as a nitrogen source to obtain the hitherto challenging five-membered heterocycles. Functionalities such as halogen, trifluoromethyl, cyano, methylthio, and heteroaryl groups were well tolerated.
