73901-09-4Relevant academic research and scientific papers
INVESTIGATION OF ISOMERIC FORMS OF 2-AMINOBENZOTHIAZOLES BY 13C NMR SPECTROSCOPY
Yagudaev, M. R.,Kosmacheva, L. P.,Ambartsumova, R. F.
, p. 1020 - 1022 (1991)
A method is presented for distinguishing the amino and imino isomers in a series of benzothiazoles by 13C NMR.It is shown, that this method is suitable for determination of the position of the side chain.
On interaction of 2-amino-benzothiazoles with halohydrins
Ambartsumova
, p. 860 - 865 (2007/10/03)
Interaction of 2-aminobenzothiazoles with ethylene chlorohydrin on boiling leads mainly to formation of the corresponding 3-(β-chloroethyl)benzothiazolin-2-ones. Reducing the reaction temperature increases the fraction of 2-imino-(3-β-hydroxyethyl)benzothiazolines. In both instances formation of bis[3-(β-hydroxyethyl)benzothiazol-2-ylidene]ammonium chlorides is observed. The reaction of 2-aminobenzothiazole with propylene bromohydrin gives only the corresponding amino alcohols. The anomalous products from the reaction of β-chloroethyl derivatives of benzothiazolinones result from a dominating side reaction of the starting 2-aminobenzothiazoles with the ethylene chlorohydrin thermolysis products that are formed on boiling. 1999 KluwerAcademic/Plenum Publishers.
Reactions of 2-aminobenzothiazoles with ethylene chlorohydrin, molecular and crystal structure of bis[(3-β-hydroxyethyl)benzothiazolyl-2-endene]ammonium chloride
Makhmudov,Ambartsumova,Tashkhodzhaev
, p. 1095 - 1099 (2007/10/03)
Hydroxyethylation of 2-aminobenzothiazoles by ethylene chlorohydrin unexpectedly led to preferential formation of 3-β-chloroethylbenzothiazolin-2-one. In the case of unsubstituted 2-aminobenzothiazole, we also isolated the target 2-imino-3-β-hydroxyethylbenzothiazoline and bis[(3-β-hydroxyethyl)benzothiazolyl-2-indene]ammonium chloride. As a result of reaction of 2-aminobenzothiazole with 3-β-chloroethylbenzothiazolin-2-one, we obtained 2-(benzothiazolyl-2-imino)-3-[β-(2-oxobenzothiazolin-3-yl)ethyl] benzothiazoline. The structure of the synthesized compounds was established based on x-ray diffraction, PMR, IR, UV, and mass spectra. 1997 Plenum Publishing Corporation.
