73907-94-5

Usage

Uses

Used in Organic Synthesis:
Pyrrolo[2,3-g]indazole-7,8(1H,6H)-dione is used as a key intermediate in organic synthesis for the creation of various complex organic molecules. Its unique structure allows for versatile chemical reactions, facilitating the development of new compounds with potential applications in different fields.
Used in Medicinal Chemistry:
In the pharmaceutical industry, pyrrolo[2,3-g]indazole-7,8(1H,6H)-dione is utilized as a starting material for the development of novel drugs. Its potential pharmaceutical properties have been studied extensively, with a focus on its ability to be modified and incorporated into therapeutic agents for various diseases and conditions.
Used as a Fluorescent Probe in Biological Imaging:
Pyrrolo[2,3-g]indazole-7,8(1H,6H)-dione has been investigated for its potential as a fluorescent probe in biological imaging. Its fluorescent properties can be harnessed to visualize and study biological processes at the molecular level, aiding in research and diagnostics.
Used as a Catalyst in Organic Reactions:
pyrrolo[2,3-g]indazole-7,8(1H,6H)-dione has also been explored for its potential as a catalyst in organic reactions. Its ability to facilitate and enhance the rate of chemical reactions without being consumed in the process makes it a valuable tool in the synthesis of various organic compounds.

InChI:InChI=1/C9H5N3O2/c13-8-6-5(11-9(8)14)2-1-4-3-10-12-7(4)6/h1-3,10,12H

Upstream product

• 6967-12-0 6-amino-1H-indazole 
• 77929-34-1 6-(hydroximinoacetyl)-amino-1H-indazole hydrochloride 
• 73907-93-4 6-(isonitrosoacetamido)indazole 
• 73907-93-4 2-[(E)-Hydroxyimino]-N-(1H-indazol-6-yl)-acetamide 

Downstream Products

• 73907-95-6 6-aminoindazole-7-carboxylic acid 
• 73907-96-7 6-(β-benzoylthioureido)indazole-7-carboxylic acid 
• 73907-99-0 ethyl 6-aminoindazole-7-carboxylate 
• 73907-90-1 prox-benzoisoallopurinol 
• 73907-98-9 6-amino-1H-indazole-7-carboxylic acid methyl ester 
• 75844-39-2 6-amino-7-methoxycarbonyl-1-methylindazol 

Relevant academic research and scientific papers

SYNTHESIS OF A -LINKED PYRAZOLOQUINAZOLINONE

A convenient synthesis is described for pyrazoloquinazolin-9-one (4), an internally expanded benzolog of the biologically relevant pyrazolopyrimidines (2).

Synthesis of prox-Benzoisoallopurinol

Pyrazoloquinazolin-9-one (prox-benzoisoallopurinol, 1), an extented analogue of 7-hydroxypyrazolopyrimidine (isoallopurinol, 2) and a potential dimensional probe for substrates of xanthine oxidase, has been synthesized by two independent routes.The title compound, prepared by elaboration of either a suitably substituted indazole or a quinazolinone, was found to be an active substrate for and an alternative-substrate inhibitor of xanthine oxidase.The product of enzymatic oxidation of prox-benzoisoallopurinol has been identified as the corresponding prox-benzoisoalloxanthine.

Quinazoline derivatives

Novel quinazoline derivatives of the formula (1) STR1 wherein ring C is a pyrazole ring fused to ring B in two vicinal positions thereof that are not fused with ring A. The novel formula (1) compounds or pyrazolo-quinazoline-ones are structurally related to allopurinol, a well known drug useful in the treatment of gout and are expected to replace or complement allopurinol in the therapeutic use thereof. The generic name Benzoallopurinol is suggested for the novel formula (1) compounds; formula (1) includes angular and linear structures of the interfused rings A, B and C. Two methods for producing the novel formula (1) compounds are disclosed. The first method starts from the indazole structure that includes the interfused rings B and C, and ring A is formed on the indazole moiety. The second method starts from the quinazoline structure that includes interfused rings A and B, and the pyrazole ring C is formed on the benzo moiety (ring B) of the quinazoline structure. Either method may lead to angular or linear benzoallopurinols depending upon the substituents introduced into the starting structure for forming the complemental ring thereon.