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Usage

Uses

Used in Pharmaceutical Industry:
2-Oxo-cycloheptanecarbonitrile serves as a crucial intermediate in the synthesis of various pharmaceutical compounds. Its unique structure allows for the development of new drugs with potential therapeutic applications, contributing to advancements in medicine.
Used in Agrochemical Industry:
In the agrochemical sector, 2-Oxo-cycloheptanecarbonitrile is utilized as an intermediate for the production of pesticides and other agrochemicals. Its involvement in the synthesis of these compounds aids in enhancing crop protection and yield.
Used in Specialty Chemicals Production:
2-Oxo-cycloheptanecarbonitrile is employed in the creation of specialty chemicals, which are high-value compounds used in specific applications due to their unique properties. Its role in this industry is vital for the development of tailored chemical solutions for niche markets.
Used in Research and Development:
2-Oxo-cycloheptanecarbonitrile is also used as a key component in research and development initiatives. It is instrumental in the exploration of new materials and chemical products, driving innovation and discovery in the scientific community.

Upstream product

• 14092-11-6 1-pyrrolidino-1-cycloheptene 
• 506-77-4 cyanogen chloride 
• 64799-08-2 2-formylcycloheptanone 
• 90196-80-8 α-Cyan-cycloheptanon-imid 
• 502-42-1 cycloheptanone 
• 55305-43-6 N-cyano-N-phenyl-p-toluenesulfonamide 
• 6011-14-9 2-aminoacetonitrile hydrochloride 
• 108-94-1 cyclohexanone 
• 629-40-3 octanedinitrile 

Downstream Products

• 210490-90-7 1-Benzyl-2-oxo-cycloheptanecarbonitrile 
• 59847-20-0 2-benzoyloxycycloheptanone 
• 1023754-73-5 (R)-2-((S)-tert-butoxycarbonylamino)benzyl-2-cyanocycloheptanone 
• 1039756-14-3 C₁₉H₂₈N₂O₃S 
• 1039756-13-2 N-(2-(1-cyano-2-oxocycloheptyl)ethyl)mesityl sulfonamide 
• 1123681-64-0 (S)-2-((S)-tert-butoxycarbonylamino)benzyl-2-cyanocycloheptanone 

Relevant academic research and scientific papers

Electrophilic Cyanation of Boron Enolates: Efficient Access to Various β-Ketonitrile Derivatives

The highly efficient electrophilic cyanation of boron enolates using readily available cyanating reagents, N-cyano-N-phenyl-p-toluenesulfonamide (NCTS) and p-toluenesulfonyl cyanide (TsCN), is reported. Various β-ketonitriles were prepared by this new protocol, which has a remarkably broad substrate scope compared to existing methods. The present method also allowed efficient synthesis of β-ketonitriles containing a quaternary α-carbon center. In addition, a preliminary result with the use of a chiral boron enolate for the enantioselective cyanation reaction is described.

An Alternative to the Classical α-Arylation: The Transfer of an Intact 2-Iodoaryl from ArI(O2CCF3)2

The α-arylation of carbonyl compounds is generally accomplished under basic conditions, both under metal catalysis and via aryl transfer from the diaryl λ3-iodanes. Here, we describe an alternative metal-free α-arylation using ArI(O2CCF3)2 as the source of a 2-iodoaryl group. The reaction is applicable to activated ketones, such as α-cyanoketones, and works with substituted aryliodanes. This formal C-H functionalization reaction is thought to proceed through a [3,3] rearrangement of an iodonium enolate. The final α-(2-iodoaryl)ketones are versatile synthetic building blocks.

FURO[3,2-D]PYRIMIDINE DERIVATIVES

Furo[3,2-d]pyrimidine derivatives of formula I, wherein the meanings for the various substituents are as defined in the description. These compounds are useful as H4 receptor antagonists.

A modified Robinson annulation process to α,α-disubstituted-β,γ-unsaturated cyclohexanone system. Application to the total synthesis of nanaimoal

4-Cyano-2-cyclohexenones were found to be susceptible to reductive alkylation reactions, giving the corresponding 2,2-disubstituted-3-cyclohexenone derivatives in a completely regioselective manner. This newly developed methodology has been successfully applied towards the total synthesis, in racemic form, of the marine natural product nanaimoal.