73918-71-5Relevant academic research and scientific papers
Synthesis of novel fused azecine ring systems through application of the tert-amino effect
Dunkel, Petra,Túrós, Gy?rgy,Bényei, Attila,Ludányi, Krisztina,Mátyus, Péter
experimental part, p. 2331 - 2339 (2010/06/12)
Novel fused azecine ring systems were synthesized via the microwave-assisted thermal isomerization of terphenyl or biphenyl-pyridazine compounds possessing a vinyl and a tert-amino group, through application of a new extension of the tert-amino effect. Substrates for the ring closure were prepared from ortho-dihalobenzene or pyridazinone by consecutive Suzuki couplings with ortho-sec-amino- and formylphenylboronic acids, followed by Knoevenagel condensation of the aldehydes obtained.
