739326-10-4Relevant articles and documents
Design, synthesis and evaluation of new α-nucleophiles for the hydrolysis of organophosphorus nerve agents: Application to the reactivation of phosphorylated acetylcholinesterase
Saint-Andre, Geraldine,Kliachyna, Maria,Kodepelly, Sanjeevarao,Louise-Leriche, Ludivine,Gillon, Emilie,Renard, Pierre-Yves,Nachon, Florian,Baati, Rachid,Wagner, Alain
experimental part, p. 6352 - 6361 (2011/09/19)
A series of new α-nucleophiles including oximes and amidoximes have been synthesized, and their ability to efficiently and selectively cleave the P-S bond of organophosphorus nerve agents has been evaluated. The relationship between the chemical structure