73944-53-3 Usage
Type of Compound
Alkylating agent and nitrosourea derivative
Usage
Chemotherapy drug
Cancer Treatments
Brain tumors, Hodgkin's lymphoma
Mechanism of Action
Damages the DNA of cancer cells, preventing growth and division
Administration Route
Oral
Blood-Brain Barrier
Capable of crossing, effective for brain tumor treatment
Side Effects
Bone marrow suppression, gastrointestinal toxicity
Hazardous Nature
Considered hazardous, requires extreme caution in handling
Check Digit Verification of cas no
The CAS Registry Mumber 73944-53-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,3,9,4 and 4 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 73944-53:
(7*7)+(6*3)+(5*9)+(4*4)+(3*4)+(2*5)+(1*3)=153
153 % 10 = 3
So 73944-53-3 is a valid CAS Registry Number.
73944-53-3Relevant academic research and scientific papers
Novel Antitumor Nitrosoureas and Related Compounds and Their Reactions with DNA
Lown, J. William,Joshua, Alummoottil V.,McLaughlin, Larry W.
, p. 798 - 805 (2007/10/02)
A number of nitrosoureas have been synthesized in order to examine those structural features which lead to optimum interstrand DNA cross-linking as this property may relate to their cytotoxicity and antitumor effects.The compounds include 2-chloroethyl tr
