73983-14-9Relevant articles and documents
BIARYL AMIDES WITH MODIFIED SUGAR GROUPS FOR TREATMENT OF DISEASES ASSOCIATED WITH HEAT SHOCK PROTEIN PATHWAY
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, (2019/12/04)
Provided are biaryl amides and coumarin-based compounds with modified sugar groups for treatment of diseases associated with heat shock protein pathway. The compounds having the following formulas, wherein variables are as defined herein. Formulae (I), (II), (III), (IV), and (V), Pharmaceutical compositions of the compounds are also provided. These biaryl amides and coumarin-based derivatives with modified sugar groups are useful for treatment and prevention of diseases and disorders, including neurological disorders, such as neurodegenerative diseases and nerve damaging disorders, for example, diabetic peripheral neuropathy.
CHEMICAL SYNTHESIS AND SEROREACTIVITY OF O-(3,6-DI-O-METHYL-β-D-GLUCOPYRANOSYL)-(1-4)-O-(2,3-DI-O-METHYL-α-L-RHAMNOPYRANOSYL)-(1-9)-OXYNONANOYL-BOVINE SERUM ALBUMIN - THE LEPROSY-SPECIFIC, NATURAL DISACCHARIDE-OCTYL-NEOGLYCOPROTEIN
Chatterjee, Delphi,Cho, Sang-Nae,Brennan, Patrick J.,Aspinall, Gerald O.
, p. 39 - 56 (2007/10/02)
The outer disaccharide segment, namely, O-(3,6-di-O-methyl-4B-D-glucopyranosyl)-(1-4)-2,3-di-O-methyl-α-L-rhamnopyranose, of the trisaccharide-containing, leprosy-specific, phenolic glycolipid I has been synthesized as the 8-(methoxycarbonyl)octyl glycosi