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2-amino-5-[(3,4-dichlorophenyl)amino]-6-hydroxypyrimidin-4(3H)-one is a complex organic compound with the molecular formula C10H7Cl2N5O2. It is a derivative of pyrimidin-4(3H)-one, featuring a 2-amino group, a 5-[(3,4-dichlorophenyl)amino] group, and a 6-hydroxy group. 2-amino-5-[(3,4-dichlorophenyl)amino]-6-hydroxypyrimidin-4(3H)-one is known for its potential applications in pharmaceuticals, particularly as an inhibitor of dihydrofolate reductase, an enzyme involved in the synthesis of DNA and RNA. Its chemical structure allows it to interfere with the enzyme's function, thereby inhibiting the growth of certain microorganisms and癌细胞. Due to its specific functional groups and molecular configuration, it is a subject of interest in medicinal chemistry and drug development.

7400-35-3

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7400-35-3 Usage

Classification

Non-steroidal anti-inflammatory drug (NSAID)

Previous Uses

Analgesic and antipyretic medication

Derivative of

4-aminosalicylic acid

Studied for

Treatment of inflammatory conditions, including rheumatoid arthritis and osteoarthritis

Mechanism of Action

Inhibition of cyclooxygenase enzymes, reducing production of pro-inflammatory prostaglandins

Declining Use

Due to availability of safer and more effective NSAIDs

Adverse Effects

Gastrointestinal bleeding and nephrotoxicity

Check Digit Verification of cas no

The CAS Registry Mumber 7400-35-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,4,0 and 0 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 7400-35:
(6*7)+(5*4)+(4*0)+(3*0)+(2*3)+(1*5)=73
73 % 10 = 3
So 7400-35-3 is a valid CAS Registry Number.

7400-35-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-amino-5-(3,4-dichloroanilino)-4-hydroxy-1H-pyrimidin-6-one

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:7400-35-3 SDS

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