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N-(Benzo[1,3]dioxol-5-ylmethylene)-p-tolyl-amine is a chemical compound with the molecular formula C15H13NO2. It is an organic compound that features a benzo[1,3]dioxole ring, which is a seven-membered aromatic ring containing two oxygen atoms, and a p-tolylamine group, which is a tolylamine (an amine with a para-methylphenyl group). N-(Benzo[1,3]dioxol-5-ylmethylene)-p-tolyl-amine is known for its potential applications in the synthesis of various pharmaceuticals and organic materials due to its unique structure and reactivity. It is an important intermediate in the preparation of certain drugs and can also be used in the development of dyes and other specialty chemicals. The compound's properties, such as its solubility and stability, make it a valuable component in the field of organic chemistry and drug development.

7402-58-6

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7402-58-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 7402-58-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,4,0 and 2 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 7402-58:
(6*7)+(5*4)+(4*0)+(3*2)+(2*5)+(1*8)=86
86 % 10 = 6
So 7402-58-6 is a valid CAS Registry Number.
InChI:InChI=1/C15H13NO2/c1-11-2-5-13(6-3-11)16-9-12-4-7-14-15(8-12)18-10-17-14/h2-9H,10H2,1H3/b16-9+

7402-58-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(1,3-benzodioxol-5-yl)-N-(4-methylphenyl)methanimine

1.2 Other means of identification

Product number -
Other names N-[(E)-1,3-Benzodioxol-5-ylmethylidene]-4-methylaniline

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:7402-58-6 SDS

7402-58-6Relevant articles and documents

Visible-light-induced regioselective cross-dehydrogenative coupling of 2 H-indazoles with ethers

Singsardar, Mukta,Laru, Sudip,Mondal, Susmita,Hajra, Alakananda

, p. 4543 - 4550 (2019/04/30)

A visible-light-promoted regioselective C(sp2)-H/C(sp3)-H cross-dehydrogenative coupling between 2H-indazoles and ethers has been achieved using a catalytic amount of rose bengal as an organophotoredox-catalyst and tert-butyl hydroperoxide (TBHP) as an oxidant at ambient temperature under aerobic conditions. A variety of C-3 oxyalkylated 2H-indazoles have been synthesized in moderate to good yields. Mechanistic studies suggest a radical pathway of the present reaction.

Divergent Coupling of Alcohols and Amines Catalyzed by Isoelectronic Hydride MnIand FeIIPNP Pincer Complexes

Mastalir, Matthias,Glatz, Mathias,Gorgas, Nikolaus,St?ger, Berthold,Pittenauer, Ernst,Allmaier, Günter,Veiros, Luis F.,Kirchner, Karl

supporting information, p. 12316 - 12320 (2016/08/24)

Herein, we describe an efficient coupling of alcohols and amines catalyzed by well-defined isoelectronic hydride MnIand FeIIcomplexes, which are stabilized by a PNP ligand based on the 2,6-diaminopyridine scaffold. This reaction is an environmentally benign process implementing inexpensive, earth-abundant non-precious metal catalysts, and is based on the acceptorless alcohol dehydrogenation concept. A range of alcohols and amines including both aromatic and aliphatic substrates were efficiently converted in good to excellent isolated yields. Although in the case of Mn selectively imines were obtained, with Fe—exclusively monoalkylated amines were formed. These reactions proceed under base-free conditions and required the addition of molecular sieves.

Synthesis and biological evaluation of Ezetimibe analogs as possible cholesterol absorption inhibitors

Wang, Yubin,Haiqian,Huang, Wenlong,Zhang, Huibin,Zhou, Jinpei

scheme or table, p. 500 - 505 (2012/05/19)

In order to investigate the SAR of Ezetimibe analogs for cholesterol absorption inhibitions, amide group and electron-deficient pyridine ring were introduced to the C-(3) carbon chain of Ezetimibe. Eight new derivatives of the 2- azetidinone cholesterol absorption inhibitors have been synthesized, and all of them were enantiomerically pure. All the new compounds were evaluated for their activity to inhibit cholesterol absorption in hamsters, and most of them showed comparable effects in lowering the levels of total cholesterol in the serum.

One - Pot Reformatsky-Imine addition reaction-leading to the synthesis of structurally diverse β-lactams

Rajput, Jaspreet,Singh, Baldev,Singal, Kewal Krishan

, p. 643 - 648 (2008/09/18)

The Reformatsky-imine addition reaction of a-bromoethylacetate with aldimines derived from 3,4-methylenedioxy benzaldehyde and α- methylcinnamaldehyde has provided an efficient and practical access to structurally diverse β-lactams. All the new β-lactams

Solid-state radical reactions of 1,3-cyclohexanediones with in situ generated imines mediated by manganese(III) acetate under mechanical milling conditions

Zhang, Ze,Wang, Guan-Wu,Miao, Chun-Bao,Dong, Ya-Wei,Shen, Ye-Bing

, p. 1832 - 1833 (2007/10/03)

Under solid-state conditions, manganese(III) acetate-mediated radical reactions of 1,3-cyclohexanedione and 5,5-dimethyl-1,3-cyclohexanedione with in situ generated imines proceeded efficiently by mechanical milling at room temperature and good to excelle

Some Novel Monocyclic cis-β-Lactams from Glycine

Sharma, S. D.,Gupta, P. K.

, p. 760 - 764 (2007/10/02)

Enamine derivatives (Ia, b) obtained by the condensation of glycine and β-dicarbonyl compounds have been utilised for the stereoselective synthesis of cis-β-lactams.Addition of POCl3 to a mixture of the potassium salts (I), imines (IIa-c and III) and triethylamine gives 3-enamino-2-azetidinones (IV, VI, VII, X and XXI) in 30-40 percent yield.Imines (IId and IIe) prepared from ethyl glycinate hydrochloride and aromatic aldehydes, when subjected to this reaction yield 3-enamino-β-lactams (XIII and XVII) carrying an ester function.The protecting β-dicarbonyl function canbe easily removed with ethanol/HCl to generate the α-amino-β-lactams (V, VIII, XI, XIV, XVIII and XXII) which have been used as the progenitors for the preparation of 3-amido-2-azetidinones.The α-amido-β-lactams (XV and XIX) having an ester function on treatment with 0.1 N NaOH in acetone get converted into the novel α-amido-β-lactams (XVI and XX) carrying a free carboxy function essential for antibacterial activity.

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