74034-56-3 Usage
Uses
Used in Pharmaceutical Industry:
9ALPHA,11ALPHA-METHYLENE-15S-HYDROXY-11A-DEOXY-11A-METHYLENE-THROMBA-5Z,13E-DIEN-1-OIC ACID is used as a therapeutic agent for the treatment of cardiovascular diseases. Its potent coronary vasoconstrictor properties and ability to inhibit platelet aggregation make it a valuable compound in the development of medications targeting conditions such as thrombosis and atherosclerosis.
Used in Research Applications:
In the field of medical research, 9ALPHA,11ALPHA-METHYLENE-15S-HYDROXY-11A-DEOXY-11A-METHYLENE-THROMBA-5Z,13E-DIEN-1-OIC ACID serves as an important tool for studying the mechanisms of thromboxane-mediated vasoconstriction and platelet aggregation. Its selective and dose-dependent inhibition of TXB2 synthesis in rabbit platelets allows researchers to investigate the role of thromboxane in various physiological and pathological processes.
Used in Drug Development:
9ALPHA,11ALPHA-METHYLENE-15S-HYDROXY-11A-DEOXY-11A-METHYLENE-THROMBA-5Z,13E-DIEN-1-OIC ACID is utilized in the development of new drugs targeting thromboxane receptors. Its unique properties, such as converting the thromboxane synthase (TXAS) heme cofactor to its 5-coordinate form, provide a basis for designing novel therapeutic agents with improved efficacy and reduced side effects in the treatment of cardiovascular diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 74034-56-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,4,0,3 and 4 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 74034-56:
(7*7)+(6*4)+(5*0)+(4*3)+(3*4)+(2*5)+(1*6)=113
113 % 10 = 3
So 74034-56-3 is a valid CAS Registry Number.
74034-56-3Relevant academic research and scientific papers
SYNTHESIS OF THROMBOXANE A2 ANALOGS-1. (+/-)-DIMETHANOTHROMBOXANE A2
Ohuchida, Shuichi,Hamanaka, Nobuyuki,Hayashi, Masaki
, p. 4257 - 4262 (2007/10/02)
The stable thromboxane A2 analog (+/-)-dimethanothromboxane A2 1 was synthesized from bicycloheptane 2 via the tricyclic compound 4.