74063-26-6Relevant articles and documents
Syntheses of, and structural studies on, benzo-fused 1,2,4-thiadiazines
Clark, Ewan R.,Hayward, John J.,Leontowicz, Bryce J.,Eisler, Dana J.,Rawson, Jeremy M.
, p. 1755 - 1762 (2014/03/21)
The syntheses of nine benzo-fused-1,2,4-thiadizines are reported. The use of microwave synthesis has been shown to afford high yields and short reaction times in several key reaction steps. The molecular geometries of these heterocycles are discussed and
Selective Rearrangements of 1λ4,2,4-Benzothiadiazines
Gilchrist, Thomas L.,Rees, Charles W.,Vaughan, David
, p. 55 - 59 (2007/10/02)
1-Aryl-1λ4,2,4-benzothiadiazines (1) rearrange when heated above 180 deg C to give the isomeric 4-aryl-4H-1,2,4-benzothiadiazines (2) by an intramolecular pathway, a -sigmatropic shift.The 1-phenyl-1λ4,2,4-benzoselenadiazine (4) rearranges in a similar way, but 1-alkyl- and 1-morpholino-1λ4,2,4-benzothiadiazines (6) and (8) give 2H-1,2,4-benzothiadiazines (7) with loss of the 1-substituent.On irradiation, the 1-aryl- and 1-alkyl-benzothiadiazines (1), (6), and (13) rearrange to give benzimidazoles by cleavage of the sulphur-nitrogen ylide bond; an intermediate nitrene can be intercepted by dimethyl sulphoxide.