Cas 74071-41-3,2-(4-Benzyl-piperazin-1-yl)-N-{6-[2-(4-benzyl-piperazin-1-yl)-acetylamino]-benzo[1,2-d;5,4-d']bisthiazol-2-yl}-acetamide

74071-41-3

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Basic information

Product Name: 2-(4-Benzyl-piperazin-1-yl)-N-{6-[2-(4-benzyl-piperazin-1-yl)-acetylamino]-benzo[1,2-d;5,4-d']bisthiazol-2-yl}-acetamide
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CAS NO:74071-41-3
Molecular Formula:
Molecular Weight: 654.86
EINECS: N/A
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Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: 2-(4-Benzyl-piperazin-1-yl)-N-{6-[2-(4-benzyl-piperazin-1-yl)-acetylamino]-benzo[1,2-d;5,4-d']bisthiazol-2-yl}-acetamide(CAS DataBase Reference)
NIST Chemistry Reference: 2-(4-Benzyl-piperazin-1-yl)-N-{6-[2-(4-benzyl-piperazin-1-yl)-acetylamino]-benzo[1,2-d;5,4-d']bisthiazol-2-yl}-acetamide(74071-41-3)
EPA Substance Registry System: 2-(4-Benzyl-piperazin-1-yl)-N-{6-[2-(4-benzyl-piperazin-1-yl)-acetylamino]-benzo[1,2-d;5,4-d']bisthiazol-2-yl}-acetamide(74071-41-3)

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RTECS:
HazardClass: N/A
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Hazardous Substances Data: 74071-41-3(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 74071-41-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,4,0,7 and 1 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 74071-41:
(7*7)+(6*4)+(5*0)+(4*7)+(3*1)+(2*4)+(1*1)=113
113 % 10 = 3
So 74071-41-3 is a valid CAS Registry Number.

74071-41-3Upstream product

74071-41-3Downstream Products

74071-41-3Relevant academic research and scientific papers

Bis Basic Substituted Diaminobenzobisthiazoles as Potential Antiarthritic Agents

Cullen, Ernest,Becker, Reinhold,Freter, Kurt,LeClerq, Thelma,Possanza, Genus,Wong, Hin-Chor

, p. 350 - 361 (2007/10/02)

A series of benzobisthiazoles were screened for antiinflammatory activity in the carrageenan paw edema and adjuvant arthritis tests.Compound 26, 2,6-bis(N,N-diethylamino)benzobisthiazole, was found to inhibit the swelling of the uninjected paw in the prophylactic adjuvant arthritis model with an ED50 of 2.3 mg/kg orally.As with most compounds of this series, 26 was inactive in acute model of inflammation, such as paw edema: like steroids, it showed activity in the granuloma pouch assay but did not inhibit cyclooxygenase, indicating a mode of action different from the classical nonsteroidal antiinflammatory drugs (NSAID's).At doses higher than those producing antiinflammatory activity, 26 had some immunoregulating properties.

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