74075-72-2

Upstream product

• 73663-57-7 (5-Benzo[1,3]dioxol-5-yl-oxazol-2-yl)-(3,4-dimethoxy-phenyl)-methanol 
• 266337-99-9 5-(benzo[d][1,3]dioxol-5-yl)-1,3-oxazole 
• 120-14-9 3,4-dimethoxy-benzaldehyde 

Relevant academic research and scientific papers

Oxazoles in Organic Chemistry. 2. Application to the Synthesis of Benzylisoquinoline Alkaloids

A conceptually new route to the benzylisoquinoline alkaloids has been devised.The reaction of 2-lithiooxazoles with aromatic aldehydes to generate the thermodynamically favored 2-substituted oxazoles constitutes the key step in this process.A single-pot two carbon-carbon bond-joining reaction leading to an oxazoline suitable for further transformation to a phenethylamide is also described.