740835-37-4Relevant academic research and scientific papers
Synthesis, cytotoxicity, and DNA-topoisomerase inhibitory activity of new asymmetric ureas and thioureas
Esteves-Souza, Andressa,Pissinate, Kenia,Graca Nascimento, Maria Da,Grynberg, Noema Faiga,Echevarria, Aurea
, p. 492 - 499 (2006)
A new series of N-3,3-diphenylpropyl-N-(p-X-benzyl)-N′-phenylureas (5a-g) and thioureas (6a-g) were synthesized by the reaction of secondary amines and phenyl isocyanate or isothiocyanate. The cytotoxic effects of the urea and thiourea derivatives were ev
