740853-00-3Relevant articles and documents
Natural product-guided synthesis of a spiroacetal collection reveals modulators of tubulin cytoskeleton integrity
Barun, Okram,Kumar, Kamal,Sommer, Stefan,Langerak, Anette,Mayer, Thomas U.,Mueller, Oliver,Waldmann, Herbert
, p. 4773 - 4788 (2007/10/03)
The spiro[5.5]ketal moiety forms the underlying structural skeleton of numerous biologically active natural products. Since simplified but characteristic spiroketals derived from the parent natural products retain biological activity, the spiro[5.5]ketal