74091-54-6

Basic information

• Product Name: 3-Phenyl-2,4,10-trioxa-adamantane
• Synonyms: 3-Phenyl-2,4,10-trioxa-adamantane
• CAS NO: 74091-54-6
• Molecular Weight: 218.252
• Mol File: 74091-54-6.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 3-Phenyl-2,4,10-trioxa-adamantane(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Phenyl-2,4,10-trioxa-adamantane(74091-54-6)
• EPA Substance Registry System: 3-Phenyl-2,4,10-trioxa-adamantane(74091-54-6)

Safety Data

• Hazardous Substances Data: 74091-54-6(Hazardous Substances Data)

Upstream product

• 50409-12-6 cis,cis-1,3,5-trihydroxycyclohexane 
• 707-07-3 orthobenzoic acid trimethyl ester 
• 1934-92-5 N-methyl-N-phenyl-benzamide 

Downstream Products

• 310904-10-0 cis-3,5-O-benzylidenecyclohexanol 
• 406460-97-7 (5S)-5-hydroxycyclohex-2-enone 
• 310904-17-7 (3R,5S)-methyl 3,5-O-benzylidene-6-hexadecenoate 
• 310904-12-2 (3R,5S)-3,5-O-benzylidene-1-trimethylsiloxycyclohex-1-ene 
• 310904-14-4 (3R,5S)-3,5-O-benzylidene-6-hydroxyhexanoic acid 
• 310904-15-5 (3R,5S)-methyl 3,5-O-benzylidene-6-hydroxyhexanoate 
• 310904-16-6 (3R,5S)-methyl 3,5-O-benzylidene-6-oxohexanoate 
• 310904-13-3 (3R,5S)-3,5-O-benzylidene-6-oxohexanoic acid 
• 310904-11-1 3,5-O-benzylidenecyclohexanone 
• 53951-29-4 Benzoic acid (1S,3R,5S)-3,5-dihydroxy-cyclohexyl ester 

Relevant articles and documents

Enantioselective Desymmetrization of cis-3,5- O-Arylidenecyclohexanones Catalyzed by Cinchona-Derived Quaternary Ammonium Salts

An enantioselective protocol for the desymmetrization of cis-3,5-O-arylidenecyclohexanones has been developed that proceeded under the catalysis of readily available and inexpensive Cinchona-derived quaternary ammonium salts. The synthetic relevance of the methodology was exemplified by the synthesis of a key intermediate that could be used in the preparation of the active pharmaceutical ingredient, paricalcitol (Zemplar).

Hydrolysis of trioxaadamantane ortho esters. I. Dialkoxycarbocation - ortho ester equilibrium and acidity function

3-Aryl-2,4,10-trioxaadamantane ortho esters (T) undergo a rapid equilibration with a ring opened dioxan-2-ylium ion (DH+) prior to hydrolysis to product (a 1,3,5-cyclohexanetriol monobenzoate).The cation is stable in concentrated H2SO4 solution