74093-76-8

Basic information

• Product Name: 2-Propenal, 3-(dimethylamino)-2-(phenylthio)-
• CAS NO: 74093-76-8
• Molecular Formula: C11H13NOS
• Molecular Weight: 207.296
• Mol File: 74093-76-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-Propenal, 3-(dimethylamino)-2-(phenylthio)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propenal, 3-(dimethylamino)-2-(phenylthio)-(74093-76-8)
• EPA Substance Registry System: 2-Propenal, 3-(dimethylamino)-2-(phenylthio)-(74093-76-8)

Safety Data

• Hazardous Substances Data: 74093-76-8(Hazardous Substances Data)

Upstream product

• 882-33-7 diphenyldisulfane 
• 28074-23-9 phenylsulfenyl bromide 
• 927-63-9 3-dimethylaminoacrolein 
• 73312-69-3 2-chloro-3-(N,N-dimethylamino)acrylaldehyde 
• 108-98-5 thiophenol 

Downstream Products

• 121487-11-4 2-tert-butyldimethylsilyloxy-5-phenylthiopyrimidine 
• 90584-76-2 N-(3-(Dimethylamino)-2-(phenylthio)-2-propenylidene)-N-methylmethanaminium Perchlorate 
• 74093-90-6 5-phenylthio-2(1H)-pyrimidinone 

Relevant articles and documents

Lithiation and Thiylation of 5-Bromopyrimidines

5-Thiylated pyrimidines have been prepared by cyclization reactions, and by reactions involving lithiated pyrimidine intermadiates. tert-Butyldimethylsilyl, trimethylsilyl, isopropyl and tert-butyl groups have been tried as O-protecting groups in the lithiation of 5-bromo-2(1H)-pyrimidinone.The trimethylsilyl group is cleaved during lithiation and the tert-butyldimethylsilyl group is cleaved by thiolates generated from disufides during the thiylation. tert-Butyldimethylsilyl chloride together with a base in dichloromethane was used for O-silylation of pyrimidin-2-ones. tert-Butyldimethylsilyl 2-pyrimidinyl ethers are cleaved by acetic acid in chloroform.