741-81-1Relevant academic research and scientific papers
Reaction of 1,3-Dialkylbarbituric acids with aliphatic amines
Krasnov
, p. 280 - 284 (2007/10/03)
On heating triethylammonium 1,3-dimethylbarbiturate, 1,3-dimethylthiobarbiturate, and 1,3-diphenylbarbiturate occurs dealkylation of triethylamine to afford in high yields the corresponding 5-ethyl substituted barbituric acids. The cleavage of alkyl groups happened also efficiently with tributyl, tribenzyl, and dimethylbenzylammonium salts, and less efficiently with trimethylammonium and diethylammonium salts. These reactions are characteristic only of 1.3-disubstituted barbituric acids; the barbituric acid and its 1-alkyl derivatives under these conditions suffer degradation.
Ketene-S,N-acetals as Synthetic Intermediates for Heterocycles. Reaction of Ketene-S,N-acetals with Aryl Isocyanates
Takahata, Hiroki,Nakajima, Tomoko,Nakano, Masaharu,Tomiguchi, Akira,Yamazaki, Takao
, p. 4299 - 4308 (2007/10/02)
Reaction of ketene-S,N-acetals (1-6), which are useful synthetic intermediates for heterocycles, with aryl isocyanates (7) is described.Annulation of 1-3 and 4-6 with 7 in boiling toluene gave bicyclic (8-10) and monocyclic (11-13) uracil derivatives, res
