741-81-1

Basic information

• Product Name: 1,3-Diphenyl-5-ethyl-2,4,6(1H,3H,5H)-pyrimidinetrione
• Synonyms: 1,3-Diphenyl-5-ethyl-2,4,6(1H,3H,5H)-pyrimidinetrione;1,3-Diphenyl-5-ethylbarbituric acid
• CAS NO: 741-81-1
• Molecular Formula: C₁₈H₁₆N₂O₃
• Molecular Weight: 308.33
• Mol File: 741-81-1.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 437.9°C at 760 mmHg
• Flash Point: 188.3°C
• Appearance: /
• Density: 1.263g/cm³
• Vapor Pressure: 7.2E-08mmHg at 25°C
• Refractive Index: 1.606
• CAS DataBase Reference: 1,3-Diphenyl-5-ethyl-2,4,6(1H,3H,5H)-pyrimidinetrione(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Diphenyl-5-ethyl-2,4,6(1H,3H,5H)-pyrimidinetrione(741-81-1)
• EPA Substance Registry System: 1,3-Diphenyl-5-ethyl-2,4,6(1H,3H,5H)-pyrimidinetrione(741-81-1)

Safety Data

• Hazardous Substances Data: 741-81-1(Hazardous Substances Data)

Usage

InChI:InChI=1/C18H16N2O3/c1-2-15-16(21)19(13-9-5-3-6-10-13)18(23)20(17(15)22)14-11-7-4-8-12-14/h3-12,15H,2H2,1H3

Upstream product

• 601-75-2 ethylmalonic acid 
• 102-07-8 bis(diphenyl)urea 
• 103-71-9 phenyl isocyanate 
• 7391-60-8 1,3-diphenylbarbituric acid 
• 121-44-8 triethylamine 
• 93251-15-1 6-Dimethylamino-5-ethyl-1,3-diphenyl-1H-pyrimidine-2,4-dione 

Relevant articles and documents

Reaction of 1,3-Dialkylbarbituric acids with aliphatic amines

On heating triethylammonium 1,3-dimethylbarbiturate, 1,3-dimethylthiobarbiturate, and 1,3-diphenylbarbiturate occurs dealkylation of triethylamine to afford in high yields the corresponding 5-ethyl substituted barbituric acids. The cleavage of alkyl groups happened also efficiently with tributyl, tribenzyl, and dimethylbenzylammonium salts, and less efficiently with trimethylammonium and diethylammonium salts. These reactions are characteristic only of 1.3-disubstituted barbituric acids; the barbituric acid and its 1-alkyl derivatives under these conditions suffer degradation.

KETENE-S,N-ACETALS AS INTERMEDIATES OF HETEROCYCLES. NEW SYNTHESIS OF URACIL AND BARBITURIC ACID DERIVATIVES

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