74112-34-8Relevant academic research and scientific papers
Asymmetric hydrogenation of α,β-unsaturated ketones catalyzed by Ru-TPPTS-(S,S)-DPENDS complex in ionic liquids
Wang, Jinbo,Qin, Ruixiang,Fu, Haiyan,Chen, Jun,Feng, Jian,Chen, Hua,Li, Xianjun
, p. 847 - 851 (2008/01/13)
The asymmetric hydrogenation of α,β-unsaturated ketones catalyzed by the achiral ruthenium monophosphine complex RuCl2(TPPTS)2 [TPPTS: P(m-C6H4SO3Na)3] modified by (S,S)-DPENDS [disodium salt of sulfonated (S,S)-1,2-diphenyl-1,2-ethylene-diamine] was investigated in ionic liquid [RMIM]Ts (1-alkyl-3-methylimidazolium p-methylphenylsulfonates, R = ethyl, butyl, octyl, dodecyl). Chemoselectivity of 100% and 75.9% ee were obtained for benzalacetone under the optimized conditions. The resulting products can be easily separated from the catalyst immobilized in ionic liquid [EMIM]Ts by extraction with n-hexane, while the catalyst can be reused seven times without the loss of catalytic activity and enantioselectivity. Especially, the addition of water can improve the performance of the catalyst.
