74113-07-8Relevant academic research and scientific papers
Stereospecific Alkylation of 3,5,5-Trisubstituted-4-hydroxy-1-p-tosyl-2-pyrazolines by Trimethylaluminum. An Efficient Synthesis of 3,3,5,5-Tetrasubstituted-1-pyrazolin-4-ones
Pirkle, William H.,Hoover, Dennis J.
, p. 3407 - 3413 (2007/10/02)
Isomeric p-tosylpyrazolines 5 and 6 are obtained in high yield by cyclization of the tosylhydrazones of various β,β-disubstituted-α,β-epoxy ketones 4.Oxidation of these mixtures to pyrazolones 9 followed by selective reduction affords isomers 5.Reaction o
