74115-08-5 Usage
Uses
SKF 83822 is a dopamine D1-like receptor agonist.
Biological Activity
High affinity, selective dopamine D 1 -like receptor agonist. K i values are 3.2, 3.1, 186, 66, 335, 1167, 1251 and 1385 nM at recombinant D 1 , D 5 , D 2 , D 3 , D 4 , 5-HT 2A , α 1A and α 1B receptors respectively. Stimulates adenylyl cyclase (EC 50 = 65 nM) but not phosphoinositide hydrolysis. Induces extreme arousal and hyperlocomotion following subcutaneous administration in monkeys.
Check Digit Verification of cas no
The CAS Registry Mumber 74115-08-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,4,1,1 and 5 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 74115-08:
(7*7)+(6*4)+(5*1)+(4*1)+(3*5)+(2*0)+(1*8)=105
105 % 10 = 5
So 74115-08-5 is a valid CAS Registry Number.