74123-20-9

Usage

Uses

Used in Pharmaceutical Industry:
Trifluoromethylacetate is used as a reagent in organic synthesis for its capacity to introduce the trifluoromethyl group into pharmaceutical compounds. This modification can improve the pharmacokinetic and pharmacodynamic properties of drugs, leading to enhanced efficacy and safety profiles.
Used in Agrochemical Industry:
In the agrochemical sector, Trifluoromethylacetate serves as a reagent to incorporate the trifluoromethyl group into agrochemical compounds. This can result in improved pest control agents with better stability and lower environmental impact.
Used in Material Science:
Trifluoromethylacetate is utilized as a building block in the development of novel materials. Its introduction into material structures can enhance properties such as chemical resistance, thermal stability, and other desirable characteristics for various applications.
Used in Research and Development:
As a potential candidate for the development of new pharmaceuticals and materials, Trifluoromethylacetate is used in research and development settings to explore its capabilities and potential applications in creating innovative products with improved properties.

Upstream product

• 60-29-7 diethyl ether 
• 115464-59-0 methyltrifluoromethyldioxirane 

Relevant academic research and scientific papers

DECOMPOSITION OF DIOXIRANES INDUCED BY DIALKYL ETHERS

Simple dialkyl ethers (i.e. diethyl or dihexyl ether), in addition to undergo oxidative cleavage by reaction with methyl(trifluoromethyl)dioxirane or dimethyldioxirane, induce the decomposition of these oxidation reagents in a concentration dependent manner.The identification of compounds derived from reactions with species such as CH3. or CF3CO2. suggests that the above decomposition is a radical chain process.Key words: Ether, radicals, dimethyldioxirane, methyl(trifluoromethyl)dioxirane.

Thermally and photochemically initiated radical chain decomposition of ketone-free methyl(trifluoromethyl)dioxirane

Ketone-free solutions of methyl(trifluoromethyl)dioxirane (1) were obtained for the first time in several inert solvents, which enabled the study of the thermal and photochemical decompositions of dioxirane 1 in gas, solution, and matrix phases. Vacuum flash pyrolysis of dioxirane 1 afforded exclusively methyl trifluoroacetate (3a). Both gas- and liquid-phase photolyses and thermal liquid-phase decomposition of dioxirane 1 involve a radical chain process, initiated by attack of CH3 and CF3 radicals on dioxirane 1 to give α-alkoxy-substituted alkoxy radicals as intermediates; the latter are responsible for the production of esters 3a-d. Matrix-phase photolysis of dioxirane 1 led to methyl trifluoroacetate (3a) and 1,1,1 -trifluoroethane as main products, while gas-phase pyrolysis gave exclusively the ester 3a.