741263-58-1

Upstream product

• 40596-30-3 (E)-1-chloro-2,4-pentadiene 
• 55022-46-3 4-methyl-N-prop-2-ynylbenzenesulfonamide 
• 922-65-6 divinylcarbinol 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 1222835-09-7 C₂₂H₂₇NO₄S 
• 1210796-10-3 (E)-N-(5,5-diphenylpent-4-en-2-ynyl)-4-methyl-N-(penta-2,4-dienyl)benzenesulfonamide 
• 1210796-13-6 6-tosyl-6-azabicyclo[3.2.2]nona-2,8-diene 

Relevant academic research and scientific papers

Synthetic studies and mechanistic insight in nickel-catalyzed [4+2+1] cycloadditions

A new nickel-catalyzed procedure for the [4+2+1] cycloaddition of (trimethylsilyl)diazomethane with alkynes tethered to dienes has been developed, A broad range of unsaturated substrates participate in the sequence, and stereoselectivities are generally e

Preparation of allylboronates by Pd-catalysed borylative cyclisation of dienynes

Reaction of a variety of dienynes with bis(pinacolato)diboron catalysed by Pd bis(trifluoroacetate) affords allylic boronates containing five or six membered carbo- or heterocycles, by concomitant formation of one C-C and one C-B bonds. Resulting allylboronates can be employed for a variety of subsequent transformations.

Desymmetrization of meso-dienyne by asymmetric Pauson-Khand type reaction catalysts

Desymmetrization of the meso dienynes, such as propargyl 1-vinylallyl N-tosylamides (1a-c) and propargyl 1-vinylallyl ethers (1d-e), by asymmetric Pauson-Khand type reaction catalysts was studied. The corresponding vinyl substituted bicyclic pentenones (2 and 3) were obtained with high diastereoselectivity and enantioselectivity.

An efficient [4 + 2 + 1] entry to seven-membered rings

A new nickel-catalyzed procedure for the [4 + 2 + 1] cycloaddition of trimethylsilyl diazomethane with alkynes tethered to dienes has been developed. A broad range of unsaturated substrates participate in the sequence, and stereoselectivities are generall