741264-64-2Relevant articles and documents
Synthesis of potent taxoids for tumor-specific delivery using monoclonal antibodies
Miller, Michael L.,Roller, Elizabeth E.,Wu, Xinyaun,Leece, Barbara A.,Goldmacher, Victor S.,Chari, Ravi V.J.,Ojima, Iwao
, p. 4079 - 4082 (2004)
The targeted delivery of taxoids, in the form of taxane-antibody immunoconjugates, requires the preparation of taxoids containing moieties suitable for their conjugation to monoclonal antibodies. A series of taxoids incorporating a disulfide-containing li