741291-96-3Relevant academic research and scientific papers
New spirocyclic oxindole synthesis based on a hetero claisen rearrangement
Mao, Zhan,Baldwin, Steven W.
, p. 2425 - 2428 (2007/10/03)
(Equation Presented) A new method for preparing spirocyclic oxindoles is presented. Featuring a [3,3]-sigmatropic enolate rearrangement, the three-step process converts carboxylic acid starting materials to oxidnole products in overall yields of 52-76%. The enolate rearrangement step occurs at -78 °C and provides easy access to oxindole products that have previously been difficult to prepare.
Shape-tunable polymer nodules grown from liposomes via ring-opening metathesis polymerization
Jarroux, Nathalie,Keller, Patrick,Mingotaud, Anne-Francoise,Mingotaud, Christophe,Sykes, Cecile
, p. 15958 - 15959 (2007/10/03)
A new inisurf (acting as surfactant and initiator) molecule for ring-opening metathesis polymerization (ROMP) was synthesized and used in aqueous solution in order to control the size and shape of polymer nodules grown from liposomes. Nodules were observed to grow in size with conversion of monomer, and depending on the monomer used, they adopted either a spherical or comet-like shape. Here, we investigate polymer production from a liposome surface. We use a hydrophobic derivative of the Grubbs catalyst positioned at the liposome surface to allow for ROMP of monomers dissolved in the aqueous outer phase. We obtain nodules of polymer that can grow up to tens of micrometers, unveiling new efficient possibilities of polymerization from a membrane in an aqueous solution. Copyright
