741292-53-5Relevant articles and documents
Synthesis of optically active hydroxyphosphonates
Guliaiko, Irina,Nesterov, Vitaly,Sheiko, Sergei,Kolodiazhnyi, Oleg I.,Freytag, Matthias,Jones, Peter G.,Schmutzler, Reinhard
, p. 133 - 139 (2008)
The reduction of dimenthyl ketophosphonates with sodium borohydride involves asymmetric induction at the a-carbon atom, resulting in a small excess of the (R)-enantiomer of the a-hydroxyphosphonate formed. A higher ee purity was achieved if the reduction