74134-95-5

Basic information

• Product Name: 1,4-anhydro-1-(2-phenyl-2H-1,2,3-triazol-4-yl)pentitol
• CAS NO: 74134-95-5
• Molecular Formula: C₁₃H₁₅N₃O₄
• Molecular Weight: 277.2759
• Mol File: 74134-95-5.mol

Chemical Properties

• Boiling Point: 576.7°C at 760 mmHg
• Flash Point: 302.6°C
• Density: 1.58g/cm³
• Vapor Pressure: 3.85E-14mmHg at 25°C
• Refractive Index: 1.716
• CAS DataBase Reference: 1,4-anhydro-1-(2-phenyl-2H-1,2,3-triazol-4-yl)pentitol(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-anhydro-1-(2-phenyl-2H-1,2,3-triazol-4-yl)pentitol(74134-95-5)
• EPA Substance Registry System: 1,4-anhydro-1-(2-phenyl-2H-1,2,3-triazol-4-yl)pentitol(74134-95-5)

Safety Data

• Hazardous Substances Data: 74134-95-5(Hazardous Substances Data)

Usage

Chemical class

Pentitol

Structural features

Contains a 1,2,3-triazole ring and a phenyl group

Connection

Pentitol is connected to the 1,2,3-triazole ring and phenyl group through an anhydro bridge

Potential applications

Medicinal chemistry and materials science

Unique structure

Valuable building block for the synthesis of novel compounds

Diverse activities

Biological and physicochemical activities

Research and development

Further investigation may uncover its full potential in various areas of science and technology

Upstream product

• 21238-55-1 (2R,3S,4S,5R)-2-[1,2-Bis-(phenyl-hydrazono)-ethyl]-5-hydroxymethyl-tetrahydro-furan-3,4-diol 
• 73364-71-3 (2S,3S,4S,5R)-2-[1,2-Bis-(phenyl-hydrazono)-ethyl]-5-hydroxymethyl-tetrahydro-furan-3,4-diol 
• 3624-30-4 D-manno-hept-2-ulose phenylosazone 
• 3624-30-4 D-gluco-hept-2-ulose phenylosazone 
• 21090-79-9 3,6-anhydro-D-manno-hept-2-ulose phenylosazone 

Relevant articles and documents

Studies on Anhydro-osazones. Part 5. Structure and Anomeric Configuration of the C-Nucleoside Analogues Obtained from the Dehydration of D-gluco- and D-manno-Hept-2-ulose Phenylosazones

Dehydration of D-gluco- and D-manno-hept-2-ulose phenylosazones with methanolic sulphuric acid afforded the anomeric furanosyl anhydro-osazone pair: 3,6-anhydro-D-manno-hept-2-ulose phenylosazone (2) and the gluco-analogue osazone (3).A new type of anomeric pyranosyl anhydro-osazone was also idenified.Refluxing the anhydro-osazones with copper sulphate afforded the anomeric furanosyl C-nucleoside analogues 4-α-D-arabinofuranosyl-2-phenyl-v-triazole (6) and the β-isomer (7), and the arabinofuranosyl isomers (8) and (9).The structures and anomeric configurations of the products were determined by periodate oxidation, o.r.d., and n.m.r. spectroscopy.The mechanism of the dehydration and the mass spectra of compounds (6)-(9) are discussed.

2-phenyl-1,2,3-osotriazole C-nucleoside analogs synthesis and determination of anomeric configuration

A series of anomeric 2-phenyl-1,2,3-osotriazole C-nucleoside analogs has been prepared. The anomeric configuration was determined by a novel method from the chemical shift of the C-5 proton of the osotriazole base moieties.