74136-99-5 Usage
General Description
21-(phenylseleno)progesterone is a chemical compound derived from the hormone progesterone, with the addition of a phenylseleno group. This modification gives the compound unique properties and potential therapeutic applications. Progesterone is an important hormone involved in the menstrual cycle, pregnancy, and embryogenesis. The addition of the phenylseleno group may alter the compound's activity and interactions with other proteins and receptors in the body, potentially leading to different biological effects. Research on 21-(phenylseleno)progesterone is ongoing, with potential implications for the development of novel treatments for hormone-related conditions or cancers.
Check Digit Verification of cas no
The CAS Registry Mumber 74136-99-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,4,1,3 and 6 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 74136-99:
(7*7)+(6*4)+(5*1)+(4*3)+(3*6)+(2*9)+(1*9)=135
135 % 10 = 5
So 74136-99-5 is a valid CAS Registry Number.
InChI:InChI=1/C27H34O2Se/c1-26-14-12-19(28)16-18(26)8-9-21-22-10-11-24(27(22,2)15-13-23(21)26)25(29)17-30-20-6-4-3-5-7-20/h3-7,16,21-24H,8-15,17H2,1-2H3/t21-,22-,23-,24+,26-,27-/m0/s1
74136-99-5Relevant articles and documents
Synthesis and Biochemical Screening of Phenylselenium-Substituted Steroid Hormones
Konopelski, Joseph P.,Djerassi, Carl
, p. 722 - 726 (2007/10/02)
The syntheses of phenylselenium-substituted progesterone and testosterone derivatives are described, along with data which help to establish the stereochemistry of the substituents in the testosterone molecules.Except for 21-(phenylseleno)progesterone, the molecules exhibit greatly reduced receptor-binding capabilities.
