74145-74-7Relevant academic research and scientific papers
New Diterpenes from the Common Caribbean Gorgonian Briareum asbestinum (Pallus)
Selover, Scott J.,Crews, Phillip,Tagle, Bruce,Clardy, Jon
, p. 964 - 970 (2007/10/02)
The major diterpenes in the toxic extracts of Briareum asbestinum (Pallus) from three Honduras Bay Island collections are reported.The structure and chemistry of two new asbestinins, 2 and 3, and four known ones, 4, 5, 9,and 10, are discussed.Structures for 2 and 3 were derived from spectroscopic arguments and were confirmed by chemical interconversions.NMR experiments including 13C at 90 MHz, a plot of JR/JCH with δH , and 1H spin decouplings at 360 MHz enabled assignment of all 26C's and 40 H's in 4.These data served as a standard to completely assign the 1H and 13C NMR for natural products 2, 3, 5, 9, and 10 and for synthetic products 6 and 7.
