741683-22-7

Basic information

• Product Name: 7-chloro-6-fluoro-1'-(phenylmethyl)-1H-spiro[furo[3,4-c]pyridine-3,4'-piperidine]
• Synonyms: 7-chloro-6-fluoro-1'-(phenylmethyl)-1H-spiro[furo[3,4-c]pyridine-3,4'-piperidine]
• CAS NO: 741683-22-7
• Molecular Weight: 332.805
• Mol File: 741683-22-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 7-chloro-6-fluoro-1'-(phenylmethyl)-1H-spiro[furo[3,4-c]pyridine-3,4'-piperidine](CAS DataBase Reference)
• NIST Chemistry Reference: 7-chloro-6-fluoro-1'-(phenylmethyl)-1H-spiro[furo[3,4-c]pyridine-3,4'-piperidine](741683-22-7)
• EPA Substance Registry System: 7-chloro-6-fluoro-1'-(phenylmethyl)-1H-spiro[furo[3,4-c]pyridine-3,4'-piperidine](741683-22-7)

Safety Data

• Hazardous Substances Data: 741683-22-7(Hazardous Substances Data)

Upstream product

• 741683-21-6 1'-benzylspiro[4-chloro-5-fluoro-6-azaisobenzofuran-1(3H)-4-piperidin]-3-ol 

Downstream Products

• 1017598-90-1 1'-benzyl-7-chloro-1H-spiro[furo[3,4-c]pyridine-3,4'-piperidine]-6-amine 
• 1017600-77-9 6-fluoro-1H-spiro[furo[3,4-c]pyridine-3,4'-piperidine] hydrochloride 

Relevant articles and documents

MELANIN-CONCENTRATING HORMONE RECEPTOR ANTAGONISTS CONTAINING PIPERIDINE DERIVATIVES AS THE ACTIVE INGREDIENT

The invention provides melanin-concentrating hormone receptor antagonists containing as the active ingredient piperidine derivatives represented by the general formula [I]: ???[wherein R1 is hydrogen, hydroxyl, lower alkyl, or the like; R2, R3a, R3b, R4a, R4b, R5a, R5b and R6 each stands for hydrogen, halogen, or the like; W1 and W2 each independently stands for -O-, -CH2-, or the like; Y1, Y2, Y3 and Y4 stand for -CH-, -CF-, -N-, or the like; Z stands for lower alkyl, an aliphatic heterocyclic group, or the like; Ar is a mono- or bi-cyclic aliphatic heterocycle or an aromatic heterocycle; and n is an integer of 1 to 8]. The compounds act as antagonist against melanin-concentrating hormone receptor and are useful as drugs for central diseases, circulatory diseases, or metabolic diseases.