741698-80-6

Basic information

• Product Name: N-(4-FLUOROBENZYL)-N-PROPYLAMINE
• Synonyms: CHEMBRDG-BB 9070448;N-(4-FLUOROBENZYL)-N-PROPYLAMINE;N-(4-FLUOROBENZYL)PROPAN-1-AMINE;(4-FLUOROBENZYL)PROPYLAMINE;N-(4-FLUOROPHENYLMETHYL)PROPYLAMINE;UKRORGSYN-BB BBV-086931;(4-fluorobenzyl)propylamine(SALTDATA: HCl);(4-fluorobenzyl)propylamine 1HCl
• CAS NO: 741698-80-6
• Molecular Formula: C₁₀H₁₄FN
• Molecular Weight: 167.22
• Mol File: 741698-80-6.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 217.9°C at 760 mmHg
• Flash Point: 85.6°C
• Appearance: /
• Density: 0.993g/cm³
• Vapor Pressure: 0.13mmHg at 25°C
• Refractive Index: 1.49
• CAS DataBase Reference: N-(4-FLUOROBENZYL)-N-PROPYLAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-FLUOROBENZYL)-N-PROPYLAMINE(741698-80-6)
• EPA Substance Registry System: N-(4-FLUOROBENZYL)-N-PROPYLAMINE(741698-80-6)

Safety Data

• Hazardous Substances Data: 741698-80-6(Hazardous Substances Data)

Usage

General Description

N-(4-FLUOROBENZYL)-N-PROPYLAMINE is a chemical compound with the molecular formula C11H14FN. It is a derivative of benzylamine, with a fluorine atom attached to the 4-position of the benzyl group and a propyl group attached to the terminal amine nitrogen. N-(4-FLUOROBENZYL)-N-PROPYLAMINE is commonly used in research and pharmaceutical applications as a building block for the synthesis of various organic compounds. It has also been studied for its potential pharmacological properties, including its role as a potential antidepressant and anxiolytic agent. Additionally, this chemical has been investigated for its potential use as a tool in functional brain imaging studies, particularly in relation to the serotonergic system.

InChI:InChI=1/C10H14FN/c1-2-7-12-8-9-3-5-10(11)6-4-9/h3-6,12H,2,7-8H2,1H3

Upstream product

• 349483-17-6 N-(4-fluorobenzylidene)-propan-1-amine 
• 107-10-8 propylamine 
• 459-57-4 4-fluorobenzaldehyde 
• 459-23-4 4-fluorobenzaldoxime 
• 123-38-6 propionaldehyde 

Relevant articles and documents

INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE AND METHODS OF THEIR USE

The present invention provides compounds of formula (I): wherein all of the variables are as defined herein. These compounds are inhibitors of indoleamine 2,3-dioxygenase (IDO), which may be used as medicaments for the treatment of proliferative disorders, such as cancer, viral infections and/or autoimmune diseases.

Synthesis and biological activity of some novel substituted quinazoline derivatives

A new series of 4-N-(substituted benzyl)-2-phenyl-N-propylquinazolines were synthesized. The structures of the synthesized compounds were confirmed by IR, 1H NMR, 13C NMR and mass spectral analysis. All the synthesized compounds were screened for their analgesic and anti-inflammatory activity. Among the synthesized compounds 5c, 5h and 5o exhibited significant analgesic activity at 60 and 90 minutes reading, while compounds 5g, 5k and 5l exhibited significant anti-inflammatory activity at 3rd and 4th hr reading.

Hydroamination of carbonyl compounds with oximes

N-alkyl(cycloalkyl)benzylamines, p-fluorobenzylamines, (1-phenylethyl) amines, [1-(p-fluorophenyl)ethyl]amines were synthesized by hydroamination of aldehydes and ketones with oximes.