741708-76-9Relevant academic research and scientific papers
Ring conformations of D-glucose derivatives possessing two bulky silyl protecting groups at the 3,4-positions; the first observation of a stable full-axial chair conformer without bridge structures
Yamada, Hidetoshi,Tanigakiuchi, Koki,Nagao, Kohei,Okajima, Kotaro,Mukae, Tatsuya
, p. 5615 - 5618 (2007/10/03)
The ring conformations of 3,4-bis-O-tert-butyldimethylsilyl- and 3,4-bis-O-tert-butyldiphenylsilyl-D-glucopyranoses as well as the corresponding phenyl 1-thio-D-glucopyranosides were investigated. Observations showed that the introduction of the two tert-butyldiphenylsilyl groups can flip the pyranose-ring into the 1C4 conformation possessing more axial substituents. All the substituents of the 3,4-bis-O-tert- butyldiphenylsilyl-β-D-glucopyranose were axially oriented.
