74179-53-6Relevant academic research and scientific papers
CYCLOADDITION REACTION OF 3-CYANOINDOLIZINES WITH DIMETHYL ACETYLENEDICARBOXYLATE - FORMATION OF CYCLAZINES AND 1:2 ADDUCTS
Uchida, Takane,Matsumoto, Kiyoshi
, p. 149 - 150 (2007/10/02)
3-Cyano- and 3-cyano-6,8-dimethylindolizines (1a) and (1b) react with dimethyl acetylenedicarboxylate in refluxing toluene in the presence of Pd-C to give the cyclazines (4a) and (4b), respectively, while 3-cyano-7-methyl- and 3-cyano-7-benzylindolizines (1c) and (1d) affording the 1:2 adducts (6c) and (6d) along with cyclazine (4d).
