74179-98-9Relevant academic research and scientific papers
Hindered Rotation in N,N,N'-Trisubstituted Amidines
Wolff, Hans-Michael,Hartke, Klaus
, p. 215 - 220 (1980)
Alkylation of N,N'-dimethylbenzamidine (4) with chloromethyl methyl ether and allyl iodide leads to the formation of the N-trisubstituted amidines 5a and 5d; the lithium salt of 4 yields 5b and 5c with chloromethyl methyl sulfide and (chloromethyl)diethylamin, respectively.At temperatures up to 175 deg C no sigmatropic rearrangement can be detected by (1)H-NMR spectroscopy; below room temperature a hindered rotation around the C-N single bond is observed.
