74203-36-4Relevant academic research and scientific papers
One-pot synthesis of α-substituted hydroxylamine derivatives from aldehydes using lithium perchlorate/diethyl ether as a catalyst
Heydari, Akbar,Mehrdad, Morteza,Tavakol, Hossein
, p. 1962 - 1964 (2003)
O-(Trimethylsilyl)oxime ethers, generated in situ by reaction of aldehydes and O-(trimethylsilyl)hydroxylamine in lithium perchlorate/diethyl ether solution, are highly reactive species and undergo facile reaction with silylated nucleophiles, such as trimethylsilyl cyanide and the binary reagent (MeO)3P/Me3SiCl, to give α-substituted hydroxylamine derivatives.
