742067-43-2Relevant academic research and scientific papers
Discovery of orally bioavailable cathepsin S inhibitors for the reversal of neuropathic pain
Irie, Osamu,Kosaka, Takatoshi,Ehara, Takeru,Yokokawa, Fumiaki,Kanazawa, Takanori,Hirao, Hajime,Iwasaki, Astuko,Sakaki, Junichi,Teno, Naoki,Hitomi, Yuko,Iwasaki, Genji,Fukaya, Hiroaki,Nonomura, Kazuhiko,Tanabe, Keiko,Koizumi, Shinichi,Uchiyama, Noriko,Bevan, Stuart J.,Malcangio, Marzia,Gentry, Clive,Fox, Alyson J.,Yaqoob, Mohammed,Culshaw, Andrew J.,Hallett, Allan
supporting information; experimental part, p. 5502 - 5505 (2009/08/16)
Cathepsin S inhibitors are well-known to be an attractive target as immunological therapeutic agents. Recently, our gene expression analysis identified that cathepsin S inhibitors could also be effective for neuropathic pain. Herein, we describe the effic
