742101-67-3

Upstream product

• 175165-88-5 methyl-3-methoxy-5-methyl-2-(trifluoromethanesulfonyloxy)benzoate 
• 1066-54-2 trimethylsilylacetylene 

Downstream Products

• 742101-62-8 2-ethynyl-3-methoxy-5-methyl-benzoic acid methyl ester 
• 742101-65-1 2-benzyloxy-7-[1-(2-[1,3]dioxan-2-yl-6-methoxy-4-methyl-phenyl)-vinyl]-8,8-dimethoxy-bicyclo[4.2.0]octa-1⁽⁶⁾,2,4-trien-7-ol 
• 742101-66-2 acetic acid 5-benzyloxy-2-(2-[1,3]dioxan-2-yl-6-methoxy-4-methyl-phenyl)-4-methoxy-naphthalen-1-yl ester 
• 742101-71-9 5-benzyloxy-2-(2-[1,3]dioxan-2-yl-6-methoxy-4-methyl-phenyl)-4-methoxy-naphthalen-1-ol 
• 742101-70-8 acetic acid 5-benzyloxy-2-(2-formyl-6-methoxy-4-methyl-phenyl)-4-methoxy-naphthalen-1-yl ester 
• 742101-64-0 2-[2-(1-bromo-vinyl)-3-methoxy-5-methyl-phenyl]-[1,3]dioxane 
• 742101-63-9 2-(1-bromo-vinyl)-3-methoxy-5-methyl-benzoic acid methyl ester 
• 742101-68-4 [2-(1-bromo-vinyl)-3-methoxy-5-methyl-phenyl]-methanol 
• 742101-69-5 2-(1-bromo-vinyl)-3-methoxy-5-methyl-benzaldehyde 
• 119650-51-0 1-benzyloxy-10,12-dimethoxy-8-methyl-6H-benzo[d]naphtho[1,2-b]pyran-6-one 

Relevant academic research and scientific papers

Total synthesis and structure revision of deacetylravidomycin M

Total synthesis of the unnatural enantiomer of deacetylravidomycin M was accomplished. The key steps include, (1) aryl C-glycosidation of the azido-bearing fucosyl acetate 2 by using catalytic Sc(OTf)3, (2) the [2+2] cycloaddition reaction of alkoxybenzyne bearing an azido sugar to ketene silyl acetal, and (3) the ring expansion reaction of alkoxybenzocyclobutenone. The synthesis revealed that the natural product is not the proposed amine, but the corresponding N-oxide.

Concise three-component synthesis of defucogilvocarcin M

(Matrix Presented) Concise synthesis of defucogilvocarcin M was achieved via the [2 + 2 + 2] approach to β-phenylnaphthalene structure.