742102-89-2Relevant academic research and scientific papers
Design, synthesis, and evaluation of sugar amino acid based inhibitors of protein prenyl transferases PFT and PGGT-1
El Oualid, Farid,Burm, Brigitte E. A.,Leroy, Ingrid M.,Cohen, Louis H.,Van Boom, Jacques H.,Van Den Elst, Hans,Overkleeft, Herman S.,Van Der Marel, Gijs A.,Overhand, Mark
, p. 3920 - 3923 (2007/10/03)
Eleven analogues of the C-terminal Ca1a2X motif found in natural substrates of the prenyl transferases PFT and PGGT-1 were synthesized and evaluated for their inhibition potency and selectivity against PFT and PGGT-1. Replacement of
