742105-14-2

Basic information

• Product Name: (S)-4-(6-benzyloxyindol-1-yl)-1-(tert-butyldimethylsilyloxy)butan-2-ol
• Synonyms: (S)-4-(6-benzyloxyindol-1-yl)-1-(tert-butyldimethylsilyloxy)butan-2-ol
• CAS NO: 742105-14-2
• Molecular Weight: 425.643
• Mol File: 742105-14-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (S)-4-(6-benzyloxyindol-1-yl)-1-(tert-butyldimethylsilyloxy)butan-2-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-4-(6-benzyloxyindol-1-yl)-1-(tert-butyldimethylsilyloxy)butan-2-ol(742105-14-2)
• EPA Substance Registry System: (S)-4-(6-benzyloxyindol-1-yl)-1-(tert-butyldimethylsilyloxy)butan-2-ol(742105-14-2)

Safety Data

• Hazardous Substances Data: 742105-14-2(Hazardous Substances Data)

Upstream product

• 294862-88-7 1-[2-((4S)-2,2-dimethyl-1,3-dioxolan-4-yl)ethyl]-1H-6-benzyloxyindole 
• 18162-48-6 tert-butyldimethylsilyl chloride 

Downstream Products

• 294863-03-9 1-[(R)-1-(tert-butyldimethylsilyloxy)-4-[6-(3-(4-chlorophenyl)propoxy)indol-1-yl]-2-butyl]imidazole-4-carboxamide 
• 294863-02-8 1-[(R)-1-(tert-butyldimethylsilyloxy)-4-(6-(4-phenylbutoxy)indol-1-yl)-2-butyl]imidazole-4-carboxamide 
• 294863-00-6 1-[(R)-1-(tert-butyldimethylsilyloxy)-4-(6-(3-phenylpropoxy)indol-1-yl)-2-butyl]imidazole-4-carboxamide 
• 294862-75-2 1-[(R)-4-(6-benzyloxyindol-1-yl)-1-(tert-butyldimethylsilyloxy)-2-butyl]imidazole-4-carboxamide 

Relevant articles and documents

Structure-based design, synthesis, and structure-activity relationship studies of novel non-nucleoside adenosine deaminase inhibitors

We disclose herein optimization efforts around the novel, highly potent non-nucleoside adenosine deaminase (ADA) inhibitor, 1-[(R)-1-hydroxy-4-(6-(3-(1- methylbenzimidazol-2-yl)propionylamino)indol-1-yl)-2-butyl]imidazole-4- carboxamide 1 (Ki =